| 四氟邻苯二甲酸的合成工艺改进 |
| |
| 引用本文： | 温新民,彭延庆.四氟邻苯二甲酸的合成工艺改进[J].中国药物化学杂志,1999,19(1):53-55. |
| |
| 作者姓名： | 温新民 彭延庆 |
| |
| 作者单位： | [1]济宁医学院化学室 [2]华东理工大学药物化工研究所 |
| |
| 摘 要： | 以四氯苯酐为原料，经酰亚胺化，氟化，水解得四氟邻苯二甲酸，该合成路线工艺简单、反应条件温和，总收率提高到７９％。
|
| 关 键 词： | 四氟邻苯二甲酸 中间体 合成 工艺 |
An improved synthesis of tetrafluorophthalic acid |
| |
| Wen Xinmin,Peng Yanqing,Chen Weidong.An improved synthesis of tetrafluorophthalic acid[J].Chinese Journal of Medicinal Chemistry,1999,19(1):53-55. |
| |
| Authors: | Wen Xinmin Peng Yanqing Chen Weidong |
| |
| Institution: | Wen Xinmin;
(Department of Chemistry,Ji |
| |
| Abstract: | A facile preparation of tetrafluorophthalic acid starting from tetrachlorophthalic anhydride via imidation,fluorination and hydrolysis was described.The reactions of all the steps were carried out in moderate conditions to afford an overall yield of 79%. |
| |
| Keywords: | tetrafluorophthalic acid intermediate for pharmaceuticals synthesis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
