| 小鼠B16黑色素瘤转移前后免疫器官的动态观察 |
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| 引用本文： | 丁祖玖,姚立人.小鼠B16黑色素瘤转移前后免疫器官的动态观察[J].安徽医科大学学报,1989,24(4):263-265. |
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| 作者姓名： | 丁祖玖 姚立人 |
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| 作者单位： | 安徽医科大学病理生理学教研室
(丁祖玖，姚立人，朱扬，张宝霆)，安徽医科大学病理生理学教研室(汪美初) |
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| 摘 要： | 本文报道49只小鼠(C_(57)BL)的B_(16)黑色素瘤,在发生转移前后淋巴结、脾脏、胸腺的形态变化。发现最早于接种后第4天即转移至同侧腘窝淋巴结,第6天至腹股沟淋巴结,第16天后全部淋巴结受累。本实验表明细胞免疫活性增强对肿瘤转移有抑制作用,而体液免疫活性增强对肿瘤转移可能具有促进作用。
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| 关 键 词： | 黑色素瘤 肿瘤转移 淋巴结 脾脏 胸腺 免疫细胞 |
The Dynamic Observations of Inmmuno-organs of Mice Before and After B_(16) Melanoma Metastasis |
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| Ding Zu.The Dynamic Observations of Inmmuno-organs of Mice Before and After B_(16) Melanoma Metastasis[J].Acta Universitis Medicinalis Anhui,1989,24(4):263-265. |
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| Authors: | Ding Zu |
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| Abstract: | The morphological changes in lymph node, spleen and thymus before and after metastasis of B_(16) melanoma in 49 mice (C_(57)BL) were reported.The results showed that the earliest metastasis was found on the 4th d after inoculation in the poplital node of the same side, and on the 6th d in the groin node. After the 16th d all the nodes were involed.This experiment showed that the metastasis was inhibited by the enhancement of cellular immunity, but it might be promoted by the enhancement of humoral immunity. |
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| Keywords: | melanoma neoplasm metastasis lymph nodes spleen thymus immunity cellular |
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