| GSH-Px活性与云南省地方性猝死关系的研究 |
| |
| 引用本文： | 李兴洲,王铜,冯红旗,李奇,高琳,裴俊瑞,周令望,高彦辉,邓晶,夏德义. GSH-Px活性与云南省地方性猝死关系的研究[J]. 中国地方病学杂志, 2005, 24(6): 680-681 |
| |
| 作者姓名： | 李兴洲 王铜 冯红旗 李奇 高琳 裴俊瑞 周令望 高彦辉 邓晶 夏德义 |
| |
| 作者单位： | LI Xing-zhou，WANG Tong，FENG Hong-qi，LI Qi，GAO Lin，PEI Jun-rui，ZHOU Ling-wang，GAO Yan-hui，DENG Jing，XIA De-yi. Institute of Keshan Disease，Chinese Center for Endemic Disease Control，Harbin Medical University，Harbin 150086，China |
| |
| 基金项目： | 中国疾病控制中心及卫生部委托项目（2004）：国家自然科学基金资助项目（30471497） |
| |
| 摘 要： | 目的研究云南省地方性猝死病例组与谷胱甘肽过氧化物酶（GSH—Px）活性的关系，为云南省地方性猝死的预防提供依据。方法现场调查病区大姚县、景东县、南涧县、宁蒗县及非病区大理县，采用GSH—Px活力测试盒检测患者25例、对照107例的GSH—Px活性。结果病例组GSH—Px活性高于外对照组（P〈0．05）；大姚县、景东县GSH—Px活性高于外对照大理县（P〈0．05）；宁蒗县低于大理县；宁蒗县补硒前后两次检测结果为补硒后GSH—Px活性较补硒前高（P〈0．05）。结论GSH—Px活性与云南省地方性猝死的发生可能存在一定程度的相关。
|
| 关 键 词： | 谷胱甘肽过氧化物酶（GSH—Px） 猝死 心脏 硒 克山病 |
| 文章编号： | 1000-4955（2005）06-0680-02 |
| 收稿时间： | 2005-04-07 |
| 修稿时间： | 2005-04-07 |
Study on relationship between GSH-Px activity and Yunnan endemic sudden cardiac death |
| |
| LI Xing-zhou,WANG Tong,FENG Hong-qi,LI Qi,GAO Lin,PEI Jun-rui,ZHOU Ling-wang,GAO Yan-hui,DENG Jing,XIA De-yi. Study on relationship between GSH-Px activity and Yunnan endemic sudden cardiac death[J]. Chinese Jouranl of Endemiology, 2005, 24(6): 680-681 |
| |
| Authors: | LI Xing-zhou WANG Tong FENG Hong-qi LI Qi GAO Lin PEI Jun-rui ZHOU Ling-wang GAO Yan-hui DENG Jing XIA De-yi |
| |
| Affiliation: | Institute of Keshan Disease, Chinese Center for Endemic Disease Control, Harbin Medical University, Harbin 150086, China |
| |
| Abstract: | Objective To study the difference of glutathione peroxidase (GSH-Px) activity between the patients of the Yunnan endemic sudden cardiac death(YESCD) and controls in order to provide evidence for prevention. Methods Blood GSH-Px activity of YESCD patients and controls was determined. Results GSH-Px activity of patients of YESCD was higher than that of the external controls(P < 0.05). GSH-Px activity of the disease area was higher than that of non-disease area (the external control(P < 0.05). After supplement of selenium, GSH-Px activity of the subjects in Ninglang county increased(P < 0.05). Conclusions GSH-Px activity is possibly related with YESCD to some extent. |
| |
| Keywords: | Glutathione peroxidase (GSH-Px) Death sudden cardiac Selenium Keshan disease |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
