| 高血压病肠系膜动脉平滑肌细胞端粒酶活性表达的研究 |
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| 引用本文： | 邓辉胜,吕麟亚,李家富,魏宗德,薛莉. 高血压病肠系膜动脉平滑肌细胞端粒酶活性表达的研究[J]. 泸州医学院学报, 2003, 26(1): 10-11 |
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| 作者姓名： | 邓辉胜 吕麟亚 李家富 魏宗德 薛莉 |
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| 作者单位： | 泸州医学院附属医院心血管内科,四川泸州,646000 |
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| 摘 要： | 目的 :探讨高血压病动脉平滑肌组织端粒酶活性与高血压的发病关系。方法 :采用PCR -ELISA法检测 30例高血压病患者和 2 0例血压正常者肠系膜动脉平滑肌细胞 (SMC)端粒酶活性。结果 :高血压患者端粒酶阳性表达 2 8例 (93.3% )。血压正常者端粒酶阳性表达 3例 (15 % )。差异非常显著 (P <0 .0 5 )。结论 :高血压病动脉平滑肌细胞端粒酶活性的表达升高 ,可能与高血压发病有关。
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| 关 键 词： | 高血压病 动脉平滑肌 端粒酶活性 A值 |
| 文章编号： | 1000-2669(2003)01-0010-02 |
| 修稿时间： | 2002-09-25 |
STUDY OF TELOMERASE EXPRESSION IN MESENTERIC ARTERIA SMOOTH MUSCLE CELL IN PATIENTS WITH ESSENTIAL HYPERTENSION |
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| Deng Huisheng,et al. STUDY OF TELOMERASE EXPRESSION IN MESENTERIC ARTERIA SMOOTH MUSCLE CELL IN PATIENTS WITH ESSENTIAL HYPERTENSION[J]. Journal of Luzhou Medical College, 2003, 26(1): 10-11 |
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| Authors: | Deng Huisheng et al |
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| Affiliation: | Deng Huisheng,et al Department of Cardiology,Luzhou Medical College Hospital |
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| Abstract: | Objective: To study the significance of telomerase activity in arteria smooth muscle tissue of hypertension. Methods: PCR-ELISA was applied to detect semiquantitatively the telomerase activity in 30 cases of hypertension and 20 cases of normal blood pressure. Results: Positive rate of telomerase activity was 93.3%(28/30)in hypertensive group and 15%(3/20) in normal group. The difference was significant (P<0.05). Conclusion: Telomerase activity expression of hypertension was higher than that of normal subjects in arteria smooth muscle cell of hypertension. Telomerase activity may be related with hypertension in episode. |
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| Keywords: | Hypertension Smooth muscle cell Telomerase activity A |
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