Intravenous immunoglobulin treatment for pregnancy-associated dermatomyositis |
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Authors: | Garifallia Linardaki Eleni Cherouvim Georgia Goni Kyriaki A Boki |
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Institution: | (1) Internal Medicine Registrar, Tzanio Hospital, 4 Lignadi St., Athens, 171 21, Greece;(2) Rheumatology Department, Sismanoglio Hospital, Athens, Greece |
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Abstract: | Pregnancy-associated dermatomyositis (DM) is a rare disorder, until recently treated only with corticosteroids due to the
toxicity of other immunosuppressive agents for the fetus. We present a pregnant woman with DM treated successfully with intravenous
immunoglobulin (IVIG) and medium dose corticosteroids. A 42-year-old woman presented with a rash, muscle weakness and increased
muscle enzymes on the 15th week of her first pregnancy. After the diagnosis of DM she was treated with the combination of
medium dose corticosteroids and IVIG. The patients’ symptoms resolved rapidly. No complications were noted for either her
or the fetus. Both she and her son remain disease-free after 6 years follow-up. In conclusion, IVIG treatment is a safe and
effective alternative for pregnancy-associated DM. |
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