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尿素与糖皮质激素联合治疗婴幼儿血管瘤伴血小板减少综合征
引用本文:周红林,董长宪,马玉春. 尿素与糖皮质激素联合治疗婴幼儿血管瘤伴血小板减少综合征[J]. 实用儿科临床杂志, 2007, 22(23): 1820-1821
作者姓名:周红林  董长宪  马玉春
作者单位:1. 新乡医学院研究生部,河南,新乡,453003
2. 河南省人民医院,血管瘤外科,郑州,450000
摘    要:目的探讨婴幼儿血管瘤伴血小板减少综合征(KMS)的治疗方法。方法分析2003—2006年资料完整的14例确诊为KMS患儿临床表现及治疗经过,采用自制400g/L尿素溶液与甲泼尼龙针剂联合局部注射治疗为主的综合疗法治疗,随访0.5~1.0a。结果14例中2例意外破溃行急诊手术切除,7例出现病情反复,最终12例治愈,好转、失访各1例。结论尿素与糖皮质激素联合治疗婴幼儿KMS是-种较为理想的微创治疗方法,疗效确切,不良反应小,治愈率高。

关 键 词:血管瘤  血小板减少  血管瘤伴血小板减少综合征
文章编号:1003-515X(2007)23-1820-02
修稿时间:2007-10-07

Urea Combine with Glucocorticoid Treatment of Infancy Hemangioma Associated with Thrombopenia Syndrome
ZHOU Hong-lin,DONG Chang-xian,MA Yu-chun. Urea Combine with Glucocorticoid Treatment of Infancy Hemangioma Associated with Thrombopenia Syndrome[J]. Journal of Applied Clinical Pediatrics, 2007, 22(23): 1820-1821
Authors:ZHOU Hong-lin  DONG Chang-xian  MA Yu-chun
Abstract:Objective To explore the treatment of hemangioma associated with thrombopenia(Kasabach-Merritte syndrome,KMS) in infant.Methods The clinical manifestation and the therapy of 14 cases patients with KMS in hospital from 2003 to 2006 were collected ang analyzed,the 400 g/L urea(manufactured by ourself)combined with methylprednisolone local injection were used and followed 0.5 to 1.0 year.Results Two in 14 cases were emergency exairesis,7 cases were recurred for several times,12 cases were cured,1 case was improved,1 case was loss the connection.Conclusions It is an ideal therapy method to use the urea combined with glucocorticoid to treat infancy KMS,little trauma,definite effective,low side effect,high cure rate.
Keywords:hemangioma  thrombocytopenia  hemangioma associated with thrombopenia syndrome
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