依托咪酯复合芬太尼在小儿无痛胃镜中的应用

目的：探讨依托咪酯在小儿无痛胃镜中应用的有效性及安全性。方法：30例接受无痛胃镜检查的3-10岁无并存病患儿,完全随机分成2组,一组接受芬太尼复合丙泊酚（FP组）,另一组采用芬太尼复合依托咪酯（FE组）,监测并记录2组患儿麻醉诱导前、诱导后1min、2min、5min和10min以及检查后各时点的平均动脉压、心率、血氧饱和度值;观察并记录全程不良反应及麻醉满意度及麻醉恢复情况。结果：与FP组相比,FE组患儿MAP,HR,RR,SpO2下降减少,两组差异有统计学意义。两组药物都能够提供满意的麻醉满意度及良好的麻醉后苏醒速度。结论：依托咪酯复合芬太尼在小儿无痛胃镜检查中可以提供足够的镇痛和镇静效果,且对心血管系统的影响较丙泊酚小,同时无明显不良反应。

Anesthetic Gastroscopy in Children by Combining Use of Fentanyl and Etomidate

Objective： To evaluate the efficacy and safety of anesthetic gastroscopy in children by combining use of fentanyl and etomidate. Method： 30 patients,aged 3-10 years,underwent anesthetic gastroscopy without coexist disease completely,were randomly divided into two groups,one group received fentanyl and propofol（ FP group）,another group received fentanyl and etomidate（ FE group）. The vital signs of two groups before the induction of anesthesia（ T0）,1min（ T1）,2min（ T2）,5min（ T3） and 10 min（ T4） after induction,side effects,and postoperative visual analog scale（ VAS） score were monitored and recorded. Result： Compared with the FP group,the MAP,HR,RR,SPO2in FE group were less reduced. Both group had good satisfaction about the anesthesia and recovery. Conclusion： Etomidate combined with fentanyl can provide adequate analgesia and sedation in the pediatric anesthtic gastroscopy,and the impact on the cardiovascular system is less than propofol.