肺癌术后发生呼吸功能衰竭的高危因素分析及预防探讨

目的：分析肺癌术后呼吸衰竭的危险因素并探讨其预防方法。方法：总结肺癌术后呼吸功能衰竭患者46例的临床资料，并以同期手术的92例肺癌术后未发生呼吸功能衰竭患者作对照，分析可能导致呼吸衰竭的高危因素，并探讨预防措施。结果：长期吸烟可导致患者产生术后呼衰的几率提高；术后呼衰组的肺功能指标，如肺功能肺活量（VC），最大通气量（MVV），1s用力呼气容积（FEV1）及FEV（用力呼气量）；均明显低于对照组（P＜0．05）；术后肺感染时间≤48h，患者产生术后呼衰的几率远大于肺感染时间＞48 h的患者；对患者采取全肺切除时，患者发生术后呼衰的几率高于其他两种术式。结论：肺癌术后呼吸功能衰竭发生的高危因素可根据吸烟指数、术前肺功能及手术方式来综合预测判断，并可针对性的采取预防措施，减少呼吸功能衰竭的发生。

Analysis and Prevention Risk Factors for Lung Cancer Postoperative Respiratory Failure

Objective：To analyze the risk factors of the lung cancer patients with postoperative respira-tory failure and to explore prevention for it.Method：Clinical data of 46 cases with lung cancer with postop-erative respiratory failure were analyzed .92 cases without lung cancer after surgery respiratory function fail-ure were chosen as the control.respiratory failure risk factors were analyzed and preventive measures were explore .Results：Long-term smoking can lead to patients with postoperative respiratory failure probability increased; postoperative respiratory failure group of lung function, such as lung function vital capacity （VC）, maximum voluntary ventilation （MVV）, 1s forced expiratory volume （FEV 1） and FEV （forced ex-piratory volume）; were significantly lower than the control group （P 〈0.05）; time ≤ 48 h postoperativepulmonary infection in patients with postoperative respiratory failure probability is much larger than the lunginfection in patients with〉48 h of; take on patients pneumonectomy in patients with postoperative respiratoryfailure probability is higher than the other two procedures.Conclusion： Smoking index, preoperative lungfunction and the surgical approach to comprehensive predictive judgment are lung risk factors of cancer postoperativerespiratory failure, we can targete to take preventive measures to reduce the incidence of respiratory failure.