血浆内脂素水平在多囊卵巢综合征患者中的变化及意义

探讨多囊卵巢综合征（ P COS ）患者血浆内脂素水平的变化及其临床意义。方法：回顾性分析88例PCOS患者（观察组）及60例健康妇女（对照组）的体重指数（ BMI）、血浆内脂素以及腰臀比等资料，根据BMI将两组再次分为肥胖组与非肥胖组，并在各组之间进行对比分析，同时分析PCOS患者血浆内脂素与BMI、腰臀比的相关性。结果：观察组患者肥胖率（78．4％）显著高于对照组（25．0％）（P＜0．01）；观察组BMI、血浆内脂素水平以及腰臀比均显著高于对照组（P＜0．01）；观察组内两组患者血浆内脂素水平均显著高于对照组内两组（ P＜0．01）；PCOS 患者血浆内脂素水平与BMI、腰臀比均呈显著正相关（ P＜0．05）。结论：PCOS患者血浆内脂素水平显著增高，且与BMI及腰臀比密切相关，可作为PCOS的一种新型实验室指标进行辅助诊断。

The Changes and Significance of Visfatin in Patients with Polycystic Ovarian Syndrome

To discuss the changes and significance of visfatin in patients with PCOS .Meth-od：88 patients with PCOS （ the observation group ） and 60 healthy women （ the control group ） were retro-spectively analyzed , the observation group and control group were divided into the observation obese group , observation non-obese group , control obese group , control non-obese group again according to BMI , then the BMI, plasma visfatin, and waist hip ratio（WHR） were contrasted between the groups , and the relation-ship of plasma visfatin with BMI and WHR were analyzed .Result：Obesity rate in the observation group （ 78. 4%） was significantly higher than the control group （25.0%）（ P〈0.01）; BMI, plasma visfatin, and WHR in the observation group were significantly higher than the control group （P〈0.01）;plasma visfatin in the two subgroup of the observation group was significantly higher than those in control group （ P〈0.01）; and there was a significant positive correlation between plasma visfatin BMI and WHR （P〈0.05）.Conclusion：Plasma visfatin levels were significantly increased in patients with PCOS , and closely related with BMI and WHR .So plasma visfatin can use as a new laboratory parameters in PCOS diagnosis .