老年高血压病患者血压昼夜节律与动态的动脉硬化指数的关系

目的 探讨老年高血压病患者血压昼夜节律与动态动脉硬化指数的关系。方法 根据动态血压检测结果将112例老年高血压病患者分为杓形组(n=37)、非杓形组（n=45）和反杓形组（n=30），并测定及计算动态动脉硬化指数（AASI）。结果 3组年龄,体质量指数，总胆固醇、三酰甘油、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、空腹血糖、病程和全天及白天平均收缩压、舒张压和脉压比较均无显著性差异。3组夜间平均收缩压、夜间平均舒张压、AASI比较有显著性差异（P<0.01）。结论 动态血压昼夜节律的改变与动态动脉硬化指数相关。

Relationship between day-night rhythm of blood pressure and ambulatory arterial stiffness index

AIM: To investigate the relationship between day-night rhythm of blood pressure and ambulatory arterial stiffness index (AASI) in hypertensive elderly subjects. METHODS: According to the monitoring result of ambulatory blood pressure, 112 patients were divided into three groups: dippers (n=37), non-dippers (n=45), and reverse-dippers (n=30). AASI was determined in all the patients. RESULTS: No significant differences were found among the three groups in age, body mass index, serum total cholesterol, triglyceride, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, fasting blood glucose, 24-h mean systolic blood pressure (SBP), 24-h mean diastolic blood pressure (DBP), daytime mean SBP, day time SBP, and day time mean DBP. However, significant differences were found in nighttime mean SBP, nighttime mean DBP and AASI among the three groups (P<0.01). CONCLUSION: Day/night rhythm of blood pressure and AASI are closely correlated in hypertensive elderly subjects.