HR-MRI、MRA与DSA在颅内动脉瘤瘤径测量中的对比研究

目的研究高分辨率磁共振成像(high-resolution magnetic resonance imaging,HR-MRI)在颅内动脉瘤测量中的应用价值,并与三维数字减影血管造影(three-dimensional DSA,3D-DSA)、三维时间飞跃法磁共振血管成像(threedimensional time of fl ight MRA,3D-TOF MRA)作对比。材料与方法选取2013年10月至2015年3月我院神经外科诊断为颅内动脉瘤的患者25例。患者首先行3D-TOF MRA及HR-MRI扫描,并于1周内行DSA检查。分别在3D-TOF MRA、HR-MRI和3D-DSA图像上测量动脉瘤的宽径,采用配对t检验两两比较3D-TOF MRA、HR-MRI与3D-DSA在测量颅内动脉瘤宽径方面的差异。P0.05为差异有统计学意义。结果 HR-MRI与3D-DSA、HR-MRI与3D-TOF MRA在测量颅内动脉瘤宽径方面的差异平均差值分别为(3.16±2.66)mm、(5.15±4.89)mm]均有统计学意义(P10.05,P20.05),3D-DSA与3D-TOF MRA在测量颅内动脉瘤宽径方面的差异平均差值为(2.53±5.18)mm]无统计学意义(P30.05)。结论 HRMRI与3D-DSA、HR-MRI与3D-TOF MRA在显示颅内动脉瘤宽径方面有差异,可能HR-MRI能更准确地显示颅内动脉瘤实际大小,具有较高的临床应用价值。

Comparison of HR-MRI,MRA and DSA in measuring intracranial aneurysm

AbstractObjective: To investigate the application value of high-resolution magnetic resonance imaging(HR-MRI) in measuring intracranial aneurysm by a comparative analysis with three-dimensional digital subtraction angiography (3D-DSA), three-dimensional time of flight magnetic resonance angiography (3D-TOF MRA). Materials and Methods:A total of 25 patients diagnosed of intracranial aneurysm were enrolled in department of neurosurgery of our hospital from October 2013 to March 2015. Among them, 15 cases were male and 10 female, age 5-60 years old, median age 50.5 years. Firstly all of them underwent conventional MRI sequence to verify the location of intracranial aneurysm, then 3D-TOF MRA sequence was performed, thirdly we performed HR-MRI sequence according to 3D-TOF MRA images (one patient was excluded for poor image quality). And they underwent DSA examination in a week. We measured the maximum width of intracranial aneurysm on the images of 3D-TOF MRA, HR-MRI and 3D-DSA. Statistical analysis was performed using a paired sample Student’st-test for the pairwise comparisons of the differences among HR-MRI, 3D-DSA and 3D-TOF MRA in measuring the maximum width of intracranial aneurysm. We assume the difference is significant statistically whenP<0.05.Results:In the aspect of measuring the maximum width of intracranial aneurysm, the differences between HR-MRI and 3D-DSA (the mean difference was 3.16±2.66 mm), HR-MRI and 3D-TOF MRA (the mean difference was 5.15±4.89 mm) were significant statistically (P1<0.05,P2<0.05), respectively, and there was no statistical significance between 3D-DSA and 3D-TOF MRA (the mean difference was 2.53±5.18 mm,P3>0.05).Conclusion:There were differences between HR-MRI and 3D-DSA, HR-MRI and 3D-TOF MRA in measuring the maximum width of intracranial aneurysm, HR-MRI may have higher clinical application value in measuring the actual size of intracranial aneurysm accurately.