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Diabetic patients treated with dialysis: complications and quality of life
Authors:V. R. Sørensen  E. R. Mathiesen  T. Watt  J. B. Bjorner  M. V. N. Andersen  B. Feldt-Rasmussen
Affiliation:(1) Department of Nephrology, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark;(2) Department of Endocrinology, Copenhagen University Hospital, Copenhagen, Denmark;(3) National Research Centre for the Working Environment, Copenhagen, Denmark;(4) Department of Ophthalmology, Copenhagen University Hospital, Copenhagen, Denmark
Abstract:Aims/hypothesis The aim of this study was to describe the prevalence of complications, health-related quality of life (HRQOL) and the influence of beliefs about control over health in diabetic dialysis patients. Methods Of 53 eligible diabetic patients on chronic dialysis during January 2004 in our clinic, 38 (76%) completed a kidney-specific (Kidney Disease Quality of Life) and a generic (SF-36) questionnaire and were characterised in terms of cardiovascular diseases and diabetic complications. Matched groups of non-diabetic dialysis patients (n = 40) and diabetic patients with a long duration of diabetes and normal kidney function (n = 38) served as controls. Generic HRQOL was compared with matched data from a survey on the Danish general population (n = 2248). Results Micro- and macrovascular complications were significantly more frequent in diabetic dialysis patients than in diabetic patients without renal disease. Self-rated physical health was significantly worse (p < 0.01) in diabetic dialysis patients (35 ± 9 [mean ± SD]) compared with non-diabetic dialysis patients (41 ± 10), diabetic patients with normal kidney function (45 ± 12) and the matched general population (47 ± 19). The diabetic dialysis patients had similar levels of kidney-specific quality of life and mental health compared with the control groups. Reduced physical health was predicted by the presence of end-stage renal disease, diabetes and short time spent in education. Among the diabetic patients, those who believed more on their own ability to control their diabetes and less on chance reported better mental health and were less likely to be on dialysis. Conclusions/interpretations Diabetic dialysis patients are characterised by a high prevalence of diabetic complications, reduced self-rated physical health but relatively good mental health. Electronic supplementary material The online version of this article (doi:) contains supplementary material, which is available to authorised users.
Keywords:Diabetes  Diabetic complications  Dialysis  End-stage renal disease  KDQOL  Locus of Control  Maculopathy  Quality of life  Retinopathy  SF-36
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