Disseminated sarcoidosis involving lymph nodes,bone and spleen with progressive cardiac sarcoidosis on 18F-FDG PET/CT and cardiac MRI |
| |
| Authors: | James Yuheng Jiang Veronica Chi Ken Wong James Yun Faraz Pathan Robert Mansberg |
| |
| Institution: | aDepartment of Nuclear Medicine and PET, Nepean Hospital, Kingswood, New South Wales, 2747, Australia;bDepartment of Clinical Immunology and Allergy, Nepean Hospital, Kingswood, New South Wales, 2747, Australia;cDepartment of Cardiology, Nepean Hospital, Kingswood, New South Wales, 2747, Australia;dFaculty of Medicine and Health, University of Sydney, Sydney, New South Wales, 2006, Australia |
| |
| Abstract: | A 63-year-old lady with a background of ischemic heart disease was referred for 18F-FDG PET/CT for multiple lytic bone lesions which showed disseminated FDG avid lesions in the skeleton, nodal stations as well as spleen simulating advanced malignancy such as diffuse lymphomatous disease. A diagnosis of sarcoidosis was pathologically confirmed with bone biopsy. Following treatment, repeat PET/CT revealed significant regression of FDG avid lesions, however prominent uptake in the lateral ventricular wall was suspicious for active cardiac sarcoidosis, particularly given recurrent chest pain. This was confirmed on cardiac MRI and correlation with PET enabled discrimination between ischemic and non-ischemic fibrosis. |
| |
| Keywords: | FDG PET/CT Cardiac sarcoidosis MRI CMR |
|
|
