经皮血管内支架成形术在颅内血管疾病的初步应用

目的：探讨支架置入技术在治疗颅内血管疾病中的应用价值。方法：回顾性分析了13例成功置入支架的手术经验,探讨颅内支架置入的适应证、技术可行性及并发症的预防。13例颅内血管病变包括有症状的颅内血管狭窄患者7例,其中大脑中动脉狭窄3例,颈内动脉床突上段狭窄1例,椎动脉颅内段狭窄3例;颅内宽颈动脉瘤5例,包括1例基底动脉起始段宽颈动脉瘤,2例海绵窦段巨大宽颈动脉瘤以及2例颈动脉-海绵窦瘘栓塞后海绵窦段宽颈假性动脉瘤;静脉窦狭窄1例。结果：7例有症状的颅骨血管狭窄患者在支架置入后狭窄血管明显扩张,从原来平均狭窄83％下降到5％,其中1例出现了与技术有关的并发症。5例宽颈动脉瘤患者（包括2例假性动脉瘤）通过支架辅助成功地达到了囊内栓塞。横窦狭窄患者在其一侧置入支架后,颅内压力明显下降,临床症状减轻,8个月后随访症状完全消失。结论：支架置入血管内成形技术,可以成功地应用于颅内血管疾病的治疗,但对于适应证的选择和长期的疗效有待于进一步的观察确定。

Experience with transluminal stent-assisted angioplasty for intracranial vascular diseases

OBJECTIVE: To assess the value of stent-assistant angioplasty for intracranial vascular diseases. METHODS: Thirteen patients with intracranial vascular diseases were treated consecutively by stent-assistant angioplasty for different purposes. Of these patients 7 had symptomatic intracranial artery stenosis, 3 intracranial wide-neck aneurysms, 2 intracranial pseudoaneurysms, and 1 bilateral transverse sinus stenosis. Clinical procedures and technical data of the patients were retrospectively analyzed. RESULTS: In the 7 patients, the degree of intracranial artery stenosis reduced from 83% to 5%. Three months after the operation they exhibited good patency of stented lesions. Intracranial wide neck aneurysms (with 2 pseudoaneurysms) were successfully embolized with GDC in 5 patients. The patients with bilateral transverse sinus stenosis were implanted a self-expanded stent in the right transverse sinus. One patient failed because of the tortuous configuration of the left jugular bulb, but the patient's symptoms were improved quickly after the procedure. CONCLUSION: Stent-assistant angioplasty is a useful technique for selected intracranial vascular diseases, and it needs further investigation.