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Protective Effects of Passively Transferred Merozoite-Specific Antibodies against Theileria equi in Horses with Severe Combined Immunodeficiency |
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| Authors: | Robert H Mealey Lowell S Kappmeyer Massaro W Ueti Bettina Wagner Donald P Knowles |
| Institution: | aDepartment of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington, USA;bAnimal Disease Research Unit, USDA Agricultural Research Service, Pullman, Washington, USA;cDepartment of Population Medicine and Diagnostic Science, Cornell University, Ithaca, New York, USA |
| Abstract: | Theileria equi immune plasma was infused into young horses (foals) with severe combined immunodeficiency. Although all foals became infected following intravenous challenge with homologous T. equi merozoite stabilate, delayed time to peak parasitemia occurred. Protective effects were associated with a predominance of passively transferred merozoite-specific IgG3. |
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