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Detection and phylogenetic characterization of human hepatitis E virus strains, Czech Republic
Authors:Vasickova Petra  Slany Michal  Chalupa Pavel  Holub Michal  Svoboda Radek  Pavlik Ivo
Affiliation:Author affiliations: Veterinary Research Institute, Brno, Czech Republic (P. Vasickova, M. Slany, I. Pavlik);;Charles University in Prague and University Hospital Bulovka, Prague, Czech Republic (P. Chalupa, M. Holub);;Faculty of Medicine Masaryk University and the Faculty Hospital Brno, Brno (R. Svoboda)
Abstract:To determine the origin of hepatitis E virus in the Czech Republic, we analyzed patient clinical samples. Five isolates of genotypes 3e, 3f, and 3g were obtained. Their genetic relatedness with Czech strains from domestic pigs and wild boars and patient recollections suggest an autochthonous source likely linked to consumption of contaminated pork.
Keywords:acute hepatitis E   viruses   hepatitis   phylogenetic analysis   zoonosis   public health   dispatch
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