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Pancreatic Islet Cell Amyloidosis Manifesting as a Large Pancreas
Authors:Mehmet Ruhi Onur  Mehmet Yaln?z  Ahmet Kursad Poyraz  Ibrahim Hanifi ?zercan  Yusuf Ozkan
Abstract:A 39-year-old female patient presented to our hospital with epigastric pain lasting for two months. Laboratory results showed impaired glucose tolerance. Ultrasonography of the patient showed a hypoechoic, diffusely enlarged pancreas. CT revealed a large pancreas, with multiple calcifications. On MRI, a diffusely enlarged pancreas was seen hypointense on both T1- and T2-weighted images with heterogeneous enhancement after gadolinium administration. A biopsy of the pancreas revealed primary amyloidosis of islet cells. Decreased signal on T1-weighted images without inflammation findings on CT and MRI were clues for the diagnosis.
Keywords:Pancreas  Amyloidosis  Ultrasonography  Computed tomography  Magnetic resonance imaging
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