| CDH12基因siRNA对涎腺腺样囊性癌细胞侵袭力的影响 |
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| 引用本文： | 苏柏华,王锦锋,佘林,郑斐斐,丁林灿,卢友光. CDH12基因siRNA对涎腺腺样囊性癌细胞侵袭力的影响[J]. 重庆医科大学学报, 2011, 36(1): 11-15 |
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| 作者姓名： | 苏柏华 王锦锋 佘林 郑斐斐 丁林灿 卢友光 |
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| 作者单位： | 福建医科大学附属口腔医院预防科,福州,350002 |
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| 基金项目： | 福建省科技厅科技计划重点项目 |
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| 摘 要： | 目的:探讨钙粘素12(Cadherin 12,CDH12)对涎腺腺样囊性癌(Salivary adenoid cystic carcinoma,SACC)细胞侵袭和转移能力的影响.方法:以人涎腺腺样囊性癌高转移细胞株(Salivary adenoid cystic carcinoma cell line with hi...
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| 关 键 词： | 小分子干扰RNA 钙粘素12 腺样囊性癌 侵袭 |
Role of CDH12 siRNA on invasiveness of salivary adenoid cystic carcinoma cells |
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| SU Bo-hua,et al. Role of CDH12 siRNA on invasiveness of salivary adenoid cystic carcinoma cells[J]. Journal of Chongqing Medical University, 2011, 36(1): 11-15 |
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| Authors: | SU Bo-hua et al |
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| Affiliation: | SU Bo-hua,et al(Department of Prevention,the Affiliated Stomatological Hospital,Fujian Medical University) |
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| Abstract: | Objective:To study the effect of CDH12 on invasion and migration of human salivary adenoid cystic carcinoma cells in vitro.Methods:The highly metastatic human salivary adenoid cystic carcinoma cell line SACC-M was transfected by CDH12 siRNA to silence CDH12 gene.The protein expression of CDH12,before and after siRNA transfection,was examined by Western blot.Cell growth rate was determined with Cell Counting Kit-8.At the same time,the invasive capability and migration capability were evaluated by tumour inva... |
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| Keywords: | siRNA CDH12 adenoid cystic carcinoma invasion |
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