玻璃酸钠联合关节镜清理治疗膝关节炎疗效观察

目的：探讨联合应用关节镜下关节清理术和关节腔内注射玻璃酸钠治疗膝关节炎的临床疗效。方法：膝关节骨性关节炎患者172例随机分为试验组和对照组。对照组患者实施关节镜下关节清理术，试验组在关节镜下关节清理术后给予关节腔内注射玻璃酸钠2.5 ml。对比两组患者治疗前及治疗后1周、3个月的Lequence评分、Lysholm评分和疼痛目测类比评分，以及两组治疗3个月的临床疗效。结果：治疗后1周、3个月，两组患者的Lequence评分、Lysholm评分和疼痛目测类比评分均显著低于本组前一时间点（P〈0.01）；且试验组治疗后评分显著低于对照组同期（P〈0.05或0.01）。试验组治疗3个月临床有效率显著高于对照组（P〈0.05）。结论：关节镜清理联合腔内注射玻璃酸钠治疗膝关节骨关节炎临床疗效明显，能有效改善患者症状，值得临床应用推广。

Clinical Effects of Sodium Hyaluronate Combined with Arthroscopic Debridement on Knee Osteoarthritis

Objective：To investigate the clinical effects of arthroscopic debridement combined with intra-articular injection of sodi-um hyaluronate in the treatment of knee osteoarthritis. Methods：One hundred and seventy-two cases with knee osteoarthritis were ran-domly divided into the treatment group and the control group. The control group received arthroscopic debridement, while the treatment group received intra-articular injection of 2. 5ml sodium hyaluronate after arthroscopic debridement. Lequence score, Lysholm score and visual analogue scale for pain were compared between the two groups before the treatment and after the 1-week and 3-month treatment, and the clinical effects were compared after the 3-month treatment as well. Results： Lequence score, Lysholm score and visual ana-logue pain scores after the treatment were lower than those before the treatment with significant differences （P 〈0.01） in the two groups. After the treatment,Lequence score, Lysholm score and visual analogue pain scores of the treatment group was lower than those of the control group with significant differences （P〈0. 05 or 0. 01）. After the 3-month treatment,the clinical efficacy of the treatment group was better than that of the control group （P〈0. 05）. Conclusion：Arthroscopic debridement combined with intra-articular injec-tion of sodium hyaluronate in the treatment of knee osteoarthritis has better efficacy than arthroscopic debridement alone. The combina-tion can effectively improve symptoms, which is worthy of clinical promotion.