DWI在宫颈癌诊断及预后检测的价值

目的探讨DWI在宫颈癌诊断及预后检测的价值。方法选择我院2011年1月至2014年1月收治的100例宫颈癌患者。同期选择100例宫颈癌放疗后患者及100例健康体检者,对表观扩散系数值进行分析。结果与正常宫颈管腺体相比,宫颈纤维间质的表观扩散系数值为1.70±0.45×10~(-3)mm~2/s,对比分析后,差异有统计学意义(t=6.834,P0.05)。100例宫颈癌病灶在DWI均呈现高信号状态。根据患者侵犯深度,低信号的宫颈纤维间质将会出现消失。与正常宫颈对比分析后,宫颈癌患者的表观扩散系数值为1.02±0.32×10~(-3)mm~2/s,对比分析后,差异有统计学意义(t=12.412,P0.05)。与宫颈癌患者相比,预后恢复正常患者的表观扩散系数值为1.45±0.41×10~(-3)mm~2/s,对比分析后,差异有统计学意义(t=7.395,P0.05)。与初诊宫颈癌患者相比,宫颈癌复发患者的表观扩散系数值为0.82±0.20×10~(-3)mm~2/s,对比分析后,差异有统计学意义(t=8.295,P0.05)。结论 DWI能够显著的辨别正常宫颈及宫颈癌疾病,同时还能够显著地观察到放疗后宫颈组织变化,对宫颈癌的诊断及预后具有重要的价值。

The Value of DWI in the Diagnosis and Prognosis of Cervical Cancer

Objective To investigate the diagnosis and prognosis value of DWI in detecting cervical cancer.Methods 100 patients with cervical cancer were selected from January 2011 to January 2014. 100 cases of cervical cancer radiotherapy troubles and 100 cases of healthy patients were also closed.The apparent diffusion coefficient were analyzed. Results Compared with normal cervical glands, the apparent diffusion coefficient values of cervical fibrous was 1.70±0.45×10-3mm2/s, after comparative analysis, the difference was statistically significant (t=6.834,P<0.05). 100 cases of cervical lesions in DWI showed high signal state. According to the depth of patient invasion, the low signal of cervical fiber disappeared. Compared with normal cervix, the apparent diffusion coefficient value of cervical cancer patients was 1.02±0.32×10-3mm2/s, after comparative analysis, the difference was statistically significant (t=12.412,P<0.05). Compared with patients with cervical cancer, the prognosis of patients with normal apparent diffusion coefficient value was 1.45±0.41×10-3mm2/s, after comparative analysis, the difference was statistically significant (t=7.395,P<0.05). Compared with newly diagnosed with cervical cancer, cervical cancer recurrence in patients with apparent diffusion coefficient value was 0.82± 0.20×10-3mm2/s, after comparative analysis, the difference was statistically significant (t= 8.295, P<0.05).Conclusion DWI approach can significantly distinguish normal cervix and cervical disease and it also being able to significantly observe human cervical tissue changes after radiotherapy.