2型糖尿病患者生活质量量表的研制与考评

目的： 编制适合我国2型糖尿病患者的生活质量量表。方法：根据WHO对生活质量的定义，采取结构化的决策方法从多维度筛选指标构建2型糖尿病人生活质量量表DMQLS(quality of life scale for patients with Type 2 diabetes mellitus）。应用DMQLS对236名2型糖尿病患者进行测试。结果：研制出由疾病、生理、社会、心理、满意度5个维度共87个条目的DMQLS，其中疾病维度形成2型糖尿病患者特异条目子量表，生理、社会、心理、满意度4个维度形成正常成年人群共性条目子量表。DMQLS 1周重测信度为0.996，Cronbach’s α系数为0.969，分半信度系数为0.879。因子分析提取21个公因子。 DMQLS总分与SF-36总分的相关系数为0.763，普适子量表与SF-36总分的相关系数为0.762；DMQLS总分与糖尿病特异性量表（DQOL）总分的相关系数为0.658，疾病维度与DQOL总得分的相关系数为0.615。病情程度不同的患者DMQLS总分有差别，患者治疗前后DMQLS总分有差别。结论：DMQLS是可靠、有效、灵敏的，可应用于2型糖尿病患者的生活质量评价。

Development and evaluation of quality of life scale for patients with Type 2 diabetes mellitus

OBJECTIVE: To develop a specific quality of life scale for Chinese Type 2 diabetes mellitus (DM) patients. METHODS: According to the quality of life definition of WHO, we used methods adhered to the rigorous guidelines of instrument development in item pool formation, item selection and scale validation with the data of 236 Type 2 diabetic patients recruited. RESULTS: An 87-item Quality of Life Scale for patients with Type 2 DM-prior test version ( DMQLS), including 5 domains ( disease, physical, social, psychological, and satisfaction ) was developed and showed good reliability and validity. The disease domain made up of Type 2 diabetes mellitus-specific sub-scale and the other 4 domains formed the generic sub-scale for adults. The test-retest correlation coefficient, Cronbach's Alpha coefficient and split-half reliability coefficient of DMQLS were 0.996, 0.969 and 0.879, respectively. Twenty-one common factors were extracted according to the conceptual model. The scale's correlations with SF-36 and Diabetes Quality of Life Measure ( DQOL ) were 0.763 and 0.658. DMQLS could discriminate among those with different quality of lives. CONCLUSION: DMQLS is reliable, valid and sensitive, and can be used to evaluate the curative effect of Type 2 diabetic patients.