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紫外分光光度法快速测定复方制霉素栓的含量
引用本文:郑桂英.紫外分光光度法快速测定复方制霉素栓的含量[J].中国药品标准,2000,1(2):29-31.
作者姓名:郑桂英
作者单位:湖南省药品检验所 410001
摘    要:目的:采用紫外分光光度法对制霉素中活性组份的含量测定。方法:用乙醚萃取赋形剂,制霉素用DMF溶解,再用5%DMF溶液稀释。紫外检测波长306nm。结果:通过实验方法考察,样品浓度每毫升在21-76制霉素单位范围内呈良好的线性关系。回收率为98.89/5(n=6)。结论:方法简便,灵敏,准确,可作为该制剂的快速测定方法。

关 键 词:紫外分光光度法  测定  复方制霉素栓  含量

RAPID ASSAY OF NYSFUNGIN SUPPOSITORIES BY UV SPECTROPHOTOMETRY
Authors:Zheng Guying
Institution:Hu Nan Institute for Drug Control, ChangSha 410001
Abstract:Objective: UV spectrophotometry can be applied to determination of active components in nysfungin.Method: Ethyl ether is used as extract ancillary agent.The nysfungin is solvated by DMF.then dilute it with 5%DMF solution.Detection wavelength of 306nm was specified.Results: A methodological survey pointed out there is a good linearity between 21 to 76 of nysfungin units perml.The corresponding average recovery is 98.8%(n=6).inclusion: The method was found to be simple,quick and accurate for determination of nysfungin in its suppositories.
Keywords:nysfungin  thin-layer chromatography  UV
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