Safety of mefloquine in infants with acute falciparum malaria |
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| Authors: | Dubos François Delattre Pierre Demar Magali Carme Bernard Gendrel Dominique |
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| Affiliation: | Pediatric Intensive Care Unit, Jeanne de Flandre Hospital, Lille, France. frandubos@wanadoo.fr |
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| Abstract: | We evaluated retrospectively the safety of mefloquine (25 mg/kg) for the curative treatment of uncomplicated Plasmodium falciparum malaria in 26 infants weighing <15 kg and managed during a 5-year period. Side effects were recorded in 30.8% of patients and consisted chiefly of mild and transient gastrointestinal symptoms. Mefloquine was safe in infants weighing <15 kg in our experience. |
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