| 摘 要： | Pulmonary mycosis can be seen in previously healthy individuals after submersion or near-drowning. We present two cases of the disease confirmed with histological examination in immuno-competent patients after near-drowning incidents. The submersion event in contaminated water likely increases the risk of pulmonary mycosis .Monitoring in the intensive care unit, along with the use of corticosteroids and antibiotics could have rendered our patients more vulnerable to mycosis. The definite diagnosis relies on etiological identification by fungal culture and histopathological evidence, and it may be difficult because of the lack of etiological identification. Therefore, clinical diagnosis relies on the association of a host factor, clinical course, radiological findings and microbiological findings. While optimal treatment remains undefined, the empirical early use of voriconazole has been proposed in cases of suspected scedosporiosis after near-drowning or even prophylactically in all near-drowning patients. Application of broad spectrum antifungal drugs and close monitoring for side effects are the most important contributors to favorable outcome.
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