| 青蛇藤的化学成分研究 |
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| 引用本文： | 郭红丽,周金云.青蛇藤的化学成分研究[J].中国药学杂志,2003,38(7):497-499. |
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| 作者姓名： | 郭红丽 周金云 |
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| 作者单位： | 中国医学科学院-中国协和医科大学药物研究所,北京,100050 |
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| 基金项目： | 北京市重点科技项目 ( 95 5 0 2 14 90 0 ) |
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| 摘 要： | 目的对青蛇藤的化学成分进行研究。方法应用硅胶、Sephadex LH-20柱色谱进行分离、纯化，根据理化常数和光谱分析鉴定结构。结果分离鉴定了9个化合物：4-hydroxy-3,5-dimethoxybenzoldehyde(Ⅰ)，3-methoxy-4 hydroxybenzoic acid(Ⅱ)，熊果酸(Ⅲ)，2α-羟基熊果酸(Ⅳ)，胡萝卜苷(Ⅴ)，羽扇豆醇乙酸酯(Ⅵ)，α-香树脂醇乙酸酯(Ⅶ)，大黄素甲醚(Ⅷ)，β-谷甾醇(Ⅸ)。结论上述9个化合物均为首次从青蛇藤中分离得到。
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| 关 键 词： | 青蛇藤 五环三萜 |
| 文章编号： | 1001-2494(2003)07-0497-03 |
| 收稿时间： | 2002-10-18; |
| 修稿时间： | 2002年10月18 |
Study on the chemical constituents of Periploca calophylla |
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| GUO Hong-li,ZHOU Jin-yun.Study on the chemical constituents of Periploca calophylla[J].Chinese Pharmaceutical Journal,2003,38(7):497-499. |
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| Authors: | GUO Hong-li ZHOU Jin-yun |
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| Institution: | GUO Hong-li,ZHOU Jin-yun * |
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| Abstract: | OBJECTIVE To investigate the chemical constituents of Peiploca calophylla. METHODS The constituents were isolated and purified by chromatography technology and their structures were identified on basis of spectral data. RESULTS Nine compounds were isolated and identified as 4-hydroxy-3,5-dimethoxybenzoldehyde(Ⅰ),3-methoxy-4-hydroxybenzoic acid(Ⅱ),ursolic acid(Ⅲ),2α-hydroxyursolic acid (Ⅳ),daucosterol (Ⅴ),lupeol acetate (Ⅵ),α-amyrin acetate (Ⅶ),1,8-dihydroxy-3-methoxy-6-methylanthraquinone (Ⅷ) and β-sitosterol(Ⅸ).CONCLUSION All the compounds were isolated for the first time from the plant. |
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| Keywords: | Periploca calophylla pentacyclic triterpenoids |
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