体质量管理与房颤负担关系的研究进展

肥胖和房颤（AF）是日益严峻的公共健康挑战。研究发现随着体质量指数（BMI）增加,发生AF的风险随之上升。减重不仅对于肥胖、高血压、糖耐量受损、糖尿病及阻塞性睡眠呼吸障碍等心血管危险因素皆能发挥有利效应，还可以有效改善肥胖引起的心房结构重构及电生理改变等AF发生及进展的基础因素。严谨的体质量管理策略可以有效减少AF负担。

Research progress in weight management and atrial fibrillation burden

Obesity and atrial fibrillation are increasing public health problems. Studies have shown an incremental risk of atrial fibrillation (AF) with progressive increase in body mass index (BMI). Weight loss leads to favorable changes in cardiovascular risk factors such as obesity, high blood pressure, impaired glucose tolerance, diabetes and obstructive sleep apnea, along with improvements in obesity-related structural and electrical remodeling of the atria, which forms the substrate in the development and progression of AF. A dedicated weight management strategy may result in an essential reduction of AF burden.