超重、肥胖和腹型肥胖与心血管代谢性疾病的关联研究

目的 了解超重、肥胖和腹型肥胖对心血管代谢性疾病的影响。方法 采用整群抽样方法,选取河南省开封市通许县673名15岁以上居民为调查对象进行横断面调查,并对研究对象进行问卷调查和体格检查,留取空腹和餐后2h静脉血进行血糖检测。结果 开封地区居民标化超重患病率为35.52%;标化肥胖患病率为14.18%;标化腹型肥胖患病率为42.62%。单因素logistic回归分析显示,超重、肥胖和腹型肥胖是高血压、2型糖尿病、高血脂的危险因素;腹型肥胖是冠心病和脑卒中的危险因素(P<0.05)。腹型肥胖的人群归因危险度(PAR)在高血压、2型糖尿病、高血脂和心脑血管疾病中均高于70%。结论 在对高危人群进行筛查时,腰围比体质指数更为重要。减少腹型肥胖人群比例对预防心血管代谢性疾病的意义更为重大。

Association between overweight,obesity,central obesity and cardiovascular diseases

Objective To assess the effect of overweight,obesity and central obesity on the cardiovascular disease.Methods Random sampling method was used for this cross-sectional study (673 residents aged over 15 years old).All subjects completed questionnaire and physical examination.Fasting and postprandial 2h blood samples were obtained for blood glucose detection.Results The standardized prevalence of overweight was 35.52% in Kaifeng.The standardized prevalence of obesity and central obesity were 14.18% and 42.62%,respectively.After adjusting age and gender,the univariate logistic analysis showed that overweight,obesity,and central obesity were risk factors for hypertension,type 2 diabetes and hyperlipidemia.Central obesity was a risk factor for coronary heart disease and stroke (P<0.05).The population attributable risk (PAR) of central obesity in hypertension,type 2 diabetes,hyperlipidemia and cardiac-cerebral disease were higher than 70%.Conclusion The measurement of waist circumstance is more important than body mass index when screening for high-risk groups.It is more significant to prevent cardiovascular metabolic diseases with reducing the proportion of central obesity.