| RNA干扰技术及其在肝癌治疗中的应用 |
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| 引用本文： | 杨升,卢辉山.RNA干扰技术及其在肝癌治疗中的应用[J].国际外科学杂志,2008,35(11):763-766. |
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| 作者姓名： | 杨升 卢辉山 |
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| 作者单位： | 福建医科大学附属协和医院肿瘤科,福州,350001;福建医科大学附属协和医院肿瘤科,福州,350001 |
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| 摘 要： | RNA干扰(RNAi)是指生物体内由双链RNA(dsRNA)介导同源mRNA的特异性降解,从而导致基因沉默的现象.随着研究的不断深入,RNAi在肝癌治疗中的应用也取得了积极的进展,显示着巨大的潜力,本文就此予以综述.
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| 关 键 词： | RNA干扰 肝癌 基因疗法 |
RNA interference technique and its application in liver cancer research |
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| YANG Sheng,LU Hui-Shan.RNA interference technique and its application in liver cancer research[J].International Journal of Surgery,2008,35(11):763-766. |
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| Authors: | YANG Sheng LU Hui-Shan |
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| Abstract: | RNA interference (RNAi) refers to homologous complementary messenger RNA (rnRNA)degradation induced specifically by double stranded RNA (dsRNA),which actually leads to gene silencing phenomenon.The application of RNAi technique in liver cancer gene therapy has got continual development along with deeply studying of RNAi,and showed its tremendous advantages,which are reviewed in this article. |
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| Keywords: | RNA interference liver cancer gene therapy |
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