| 地西泮治疗急性乙醇中毒不良反应的分析 |
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| 引用本文： | 陈忠庆,李小平,胡玲,程键,刘非凡.地西泮治疗急性乙醇中毒不良反应的分析[J].药物流行病学杂志,2007,16(5):288-289. |
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| 作者姓名： | 陈忠庆 李小平 胡玲 程键 刘非凡 |
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| 作者单位： | 广州军区武汉总医院急诊科,武汉,430070 |
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| 摘 要： | 目的:了解地西泮治疗急性乙醇中毒不良反应(ADR)发生情况,促进临床合理用药。方法:急诊收治的急性乙醇中毒患者应用地西泮治疗的共158例,分肌肉注射组91例和静脉注射组67例,统计分析地西泮不同给药途经治疗的不良反应。结果:肌肉注射组不良反应率为0%。静脉注射组有3例发生心跳骤停,2例发生误吸、呼吸骤停,不良反应发生率为7.46%。结论:对急性乙醇中毒患者应用地西泮镇静治疗以肌肉注射为好,静脉注射地西泮有可能诱发严重的不良反应。
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| 关 键 词： | 地西泮 乙醇中毒 急性 药物不良反应 |
| 文章编号： | 1005-0698（2007）05-0288-02 |
| 收稿时间： | 2006-11-01 |
| 修稿时间： | 2007-07-10 |
Clinical Study of Adverse Drug Reactions in Treating Acute Alcoholism with Diazepam |
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| Chen Zhongqing,Li Xiaoping,Hu Ling,Cheng Jian,Liu Feifan.Clinical Study of Adverse Drug Reactions in Treating Acute Alcoholism with Diazepam[J].Chinese Journal of Pharmacoepidemiology,2007,16(5):288-289. |
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| Authors: | Chen Zhongqing Li Xiaoping Hu Ling Cheng Jian Liu Feifan |
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| Institution: | Wuhan General Hospital of Guangzhou Military Commmand, Wuhan 430070, China |
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| Abstract: | Objective:To study the adverse drug reaction (ADR) in treating acute alcoholism with diazepam to promote rational clinical use of drugs.Method:168 patients were divided into two groups the intramuscular injection (i. m.) and the intravenous injection(i.v.).Result:No ADR occurred in the i.m.group while cardiac arrest appeared in 3 patients and aspiration or sudden breathing stops,in 2 patients,the ratio of ADR being 7.46%.Conclusion:It is better to use the intramuscular injection than the intravenous injection in treating acute alcoholism with diazepam in order to avoid se- rious ADR. |
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| Keywords: | Diazepam Acute alcoholism Adverse drug reaction |
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