Impact of dose and volume on subcutaneous fibrosis |
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| Authors: | De Santis Mario Luzi Stefano Errico Angelo Frascino Vincenzo Mangiacotti Maria Grazia Picardi Vincenzo Morganti Alessio G |
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| Affiliation: | Cattedra di Radioterapia, Università Cattolica delS. Cuore, Policlinico A. Gemelli, Largo A. Gemelli 8, 00168 Roma, Italy. dhrtp@rm.unicatt.it |
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| Abstract: | The multifactorial genesis of radiation-induced fibrosis makes a general outline of the occurence of this late toxicity fairly unpredictable. Scientific knowledge about dose fractionation, irradiated volume, total time, conformation procedures including IMRT can help provide better treatments. Chemical and physical therapies aimed at the removal of fibrosis are still limited or under study. The system of monitoring late toxicity used by the authors is presented. |
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