| 固本延衰方对亚急性衰老模型小鼠脾淋巴细胞增殖的影响 |
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| 引用本文： | 王敏 王平 王彦春 洪小平 韩永明 段妍君 邹峰. 固本延衰方对亚急性衰老模型小鼠脾淋巴细胞增殖的影响[J]. 湖北中医药大学学报, 2005, 7(3): 9-10 |
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| 作者姓名： | 王敏 王平 王彦春 洪小平 韩永明 段妍君 邹峰 |
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| 作者单位： | 湖北中医学院基础医学部,湖北,武汉,430061;广州军区武汉总医院肾内科,湖北,武汉,430070 |
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| 基金项目： | 湖北省教育厅资助青年课题2003B00001 |
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| 摘 要： | 目的探讨固本延衰方延缓亚急性衰老模型小鼠衰老的机制。方法将60只小鼠随机分为4组，除正常对照组外均皮下注射D-半乳糖造成衰老模型，并给予不同剂量的固本延衰方治疗，用MTT法测定脾淋巴细胞增殖水平。结果衰老模型组脾淋巴细胞增殖水平明显低于正常对照组（P〈0．01），固本延衰方大小剂量组脾淋巴细胞增殖水平均高于衰老模型组（P〈0．01），结论固本延衰方可提高衰老机体淋巴细胞增殖活性，从而调节免疫功能延缓衰老。
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| 关 键 词： | 固本延衰方 D-半乳糖 衰老 脾淋巴细胞增殖 |
| 文章编号： | 1008-987X（2005）03-0009-02 |
| 收稿时间： | 2005-05-25 |
| 修稿时间： | 2005-05-25 |
Influence of Guben Yanshuai Recipe on the Spleen Lymphocyte Proliferation of the Rat Model with Subacute Senility |
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| WANG Min ,WANG Ping ,WANG yarrchun,et al.. Influence of Guben Yanshuai Recipe on the Spleen Lymphocyte Proliferation of the Rat Model with Subacute Senility[J]. Journal of Hubei University of Chinese Medicine, 2005, 7(3): 9-10 |
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| Authors: | WANG Min WANG Ping WANG yarrchun et al. |
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| Affiliation: | 1. Hubei College of TCM, Wuhan 430061, 2. The Department of Internal Medicine of Nephrosis, General Hospital of Wuhan Military Area Command of Guangzhou, Wuhan 430070 |
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| Abstract: | Objective: To research the mechanism Of GubenYanshuai Fang(GBYSF) to postpone the senescence of the subacute aging model mice. Methods: 60 mices be divided into 4 groups and made aging model using D-glucose subcutaneous injection except the control group. After treating with different dosage GBYSF, We detect the spleen lymphocyte proliferation. Results:The level of spleen lymphocyte proliferation in model group is lower than that of control group(P< 0. 01),the level of spleen lymphocyte proliferation in maximum and minimum dosage of GBYSF group are higher than that of model group(P<0. 01). Conclusion: It implies that GBYSF could postpone aging from improving the level of spleen lymphocyte proliferation then regulating the body's immune function. |
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| Keywords: | GBYSF D-glucose Aging Spleen lymphocyte proliferation |
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