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Lumbar cerebrospinal fluid homovanillic acid concentrations are higher in female than male non-human primates |
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| Authors: | Richard F Seegal |
| Institution: | 1. Department of Biochemistry, Afe Babalola University, Ado-Ekiti, Nigeria;2. Department of Medical Biochemistry, Afe Babalola University, Ado-Ekiti, Nigeria;3. Department of Chemistry Education, Federal University, Oye-Ekiti, Nigeria;1. Department of Biochemistry, Afe Babalola University, PMB 5454, Ado-Ekiti, Nigeria;2. Department of Biochemistry, Bowen University, PMB 284, Iwo, Nigeria;3. Department of Biochemistry, Federal University, Oye-Ekiti, Nigeria;4. Department of Physiology, Afe Babalola University, PMB 5454, Ado-Ekiti, Nigeria;5. Department of Medical Biochemistry, Afe Babalola University, Ado-Ekiti, NIgeria |
| Abstract: | Concentrations of homovanillic acid and 5-hydroxyindoleacetic acid were determined in lumbar cerebrospinal fluid from intact male and female Macaca nemestrina. Concentrations of homovanillic acid, but not 5-hydroxyindoleacetic acid were significantly higher in the females under baseline conditions. Following probenecid treatment, 5-hydroxyindoleacetic acid concentrations were significantly elevated over baseline conditions in both sexes although only homovanillic acid concentrations were significantly higher in the female monkeys. |
| Keywords: | cerebrospinal fluid (CSF) homovanillic acid (HVA) non-human primates sexual dimorphism |
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