枸杞果汁对机体免疫作用的人体试食研究

目的:评价枸杞果汁对人体免疫系统的影响。方法:选择60名志愿者作为受试对象随机分为干预组(n=30)和安慰剂组(n=30),采用双盲法给予受试物,每日2次,每次60 ml,连续30 d。试验前后分别进行常规体检、临床症状观察、视力测定、短时注意力和记忆力测定、血清免疫指标测定。结果:志愿者饮用枸杞果汁和安慰剂30 d后,干预组临床症状有明显改善,与自身试验前及安慰剂组比较差别有统计学意义(P<0.05);干预组与安慰剂组主要症状改善总有效率分别为63.33%、20.00%,两者比较差别有统计学意义(P<0.05);干预组淋巴细胞转化能力、IL-2、IgG含量与试食前及安慰剂组试验后比较,均有显著提高(P<0.05);干预组CD4、CD8、NK、IL-4、IgA水平未见明显改变;干预组短时注意力和记忆力与试食前及安慰剂组比较差别无统计学意义;干预组视力水平未见明显改变。试验期间未见志愿者有明显不良反应,各项安全性指标均未见明显异常改变。结论:枸杞果汁能有效地调节人体免疫系统。

Study on effect of barbarum juice on human immunity

Objective:To evaluate effect of barbarum juice on human immunity.Methods: 60 volunteers were randomly divided into an interventional group(n=30) and a placebo group(n=30).These volunteers were given 60 ml test materials twice a day by bi-blind method.The course was 30 days.They were taken determinations such as routine physical examinations,clinical symptoms observing,optometry,short-term attention and memory tests,serum immune parameter before and after the experiment.Results: After the volunteers had drin...