291例宫颈病变病理会诊分析

目的 探讨宫颈上皮内瘤变的误诊原因。方法 观察291例外单位诊断为各级宫颈上皮内瘤变的会诊切片并作出诊断。结果 原诊断与会诊诊断一致的有61例（20.96%）,不一致的230例（79.04%）,不少有类宫颈上皮内瘤变样改变的病变如修复性上皮,不成熟鳞状上皮化生,萎缩等常被误诊为各级宫颈上皮内瘤变。结论 诊断宫颈上皮内瘤变时应综合观察上皮细胞的密度和分化,排列极性,核特征以及核分裂活性等改变,避免过诊断或诊断不足。

Analysis on pathological consultation of 291 cases of cervical intraepithelial neoplasia

Objective To explore the reasons for migdiagnosis of cervical intraepithelial neoplasia （CIN）. Methods Slides of 2 9 1 cases originally diagnosed as CIN （ grade I～Ⅲ ） by other hospitals were reviewed, Results The consultation diagnoses of 61 cases （20.96%） were coincided with original diagnoses, and the other 230 cases （79.04%） did not match. Many cases with changes similar to CIN, such as reparative epithelium, immature squamous metaplasia, atrophy epithelia etc, were misdiagnosed as CIN I～CIN Ⅲ or cervical carcinoma. Conclusion The changes of histological cell density, differentiation, polarity, nuclear feature and mitotic activity shall be observed in making a diagnosis of CIN, so that over - diagnosis and under-diagnosis can be avoided.