血清CA125、CEA水平检测在卵巢上皮性癌及盆腔良性肿物诊断中的价值

目的为探讨血清CA125、CEA水平在妇科卵巢上皮性癌、卵巢良性肿瘤、其它盆腔良性肿物中的升高情况及其临床意义。方法采用MPL—1型发光仪对218例妇科盆腔肿物患者的血清标本进行血清CA125、CEA水平发光检测。结果卵巢上皮性癌、盆腔结核、子宫腺肌病、卵巢子宫内膜异位症及卵泡膜—纤维组肿瘤患者其血清CA125水平中位数值、均值均高于正常,血清CEA水平只有卵巢上皮性癌中位数值、均值高于正常。结论25例卵巢上皮性癌患者血清CA125、CEA水平均升高,均值分别是455.6 U/mL、88.3 U/mL,中位数值分别是340.5 U/mL、78.1 U/mL,与其它妇科盆腔良性肿物相比有显著差异(P<0.01),有统计学意义。血清CA125、CEA水平联合检测有利于卵巢上皮性癌与其它妇科良性肿物的诊断及预后监测。

The diagnostic value of serum level of CA125、CEA in ovarian epithelial cancer and pelvic benign masses

Objective To explore the serum level of CA125、CEA in patients with ovarian epithelial cancer,ovarian benign and other pelvic benign masses,and its clinical significance.Methods Using the MPL-1 luminescent instrument to detect the serum level of CA125,CEA in serum samples of 218 gynecological patients with pelvic tumor.Results The serum level of CA125 in patients with epithelial ovarian cancer,pelvic tuberculosis,adenomyosis,ovarian endometriosis and theca-fiber tumor is higher than the normal one in the median values and average,the serum level of CEA is higher only in patients with ovarian epithelial cancer.Conclusion The serum levels of CA125 and CEA in 25 patients with epithelial ovarian cancer have risen,the mean is 455.6 U/mL、88.3 U/mL and the median value is 340.5 U/mL,78.1 U/mL,There are significant differences(P<0.01) compared to other pelvic benign tumors.So they have statistical significance.Bi-detection of serum level of CA125 and CEA will be helpful to the diagnosis and prognosis monitoring between ovarian epithelial cancer and other gynecological benign tumor.