自血混合丙球穴注疗法对哮喘豚鼠肺组织和支气管作用的光镜观察

利用光学显微镜观察自血混合丙球穴注对过敏性哮喘豚鼠肺组织和支气管形态变化的影响 ,结果表明 ,丙球加自血注射效果最好 :粘液栓基本消失 ,平滑肌未见明显痉挛、增厚 ,炎症细胞浸润大大减轻 ,支气管壁充血、水肿消失。丙球穴注也有上述作用 ,但效果一般。自血穴注效果较好 ,但稍比丙球加自血注射差。通过本实验 ,为自血混合丙球穴注治疗哮喘在临床上取得的良好疗效提供了理论依据。

Effect of Acupoint-injection of Self-blood Mixed with Gamma Globulin on the Pulmonary and Bronchial Tissues in Asthmatic Guinea Pigs

Objective: Observing the therapeutic effect of acupoint injection of self blood mixed with gamma globulin on the morphological changes of the pulmonary and bronchial tissues in allergic asthmatic guinea pigs. Methods: 51 guinea pigs were randomly divided into 1) saline intraperitoneal injection group (n=8), 2) asthma model group (n=8), 3) positive drug group (n=7), 4) self blood acupoint injection group (n=7), 5) gamma globulin acupoint injection group (n=7), 6) self blood plus gamma globulin acupoint injection group, and 7) self blood plus gamma globulin intramuscular injection group (n=7). Bilateral Feishu (BL 13) were used for injection. The injection was conducted once daily with 5 sessions being a therapeutic course, two courses altogether. Results: The results showed that the therapeutic effect of the self blood plus gamma globulin is the best, marked by basic disappearance of the muco embolism, no obvious spasm and no thickening of the smooth muscle, considerable alleviation of the inflammatory cell infiltration and disappearance of the bronchial wall congestion and edema under light microscopic observation. The injection of gamma globulin alone also had the above changes, but the effect was moderate. The effect of the self blood injection is also better, being just a little weaker than that of gamma globulin plus self blood injection. Conclusion: Acupoint injection of self blood mixed with gamma globulin has a fairly good therapeutic effect in improving the structural changes of pulmonary and bronchial tissues in asthmatic guinea pigs.