胃周转移淋巴结数对胃癌患者预后评估的价值

目的寻找适用于胃癌术后患者预后比较的简单指标。方法选取1999-2005年间在复旦大学附属中山医院胃肿瘤组接受根治性手术治疗的148例患者的病例资料进行总结，分析胃周淋巴结转移情况及其与患者预后的关系。结果148例患者3年累计总生存率为62．8％，生存率随胃周转移淋巴结数增加而下降。当胃周转移淋巴结数超过6枚时，3年生存率降至15．4％，与全组3年总生存率比较，差异有统计学意义（P〈0．01）。胃周转移淋巴结数与总阳性淋巴结数存在线性关系（r=0．94，P〈0．01），但与总切除淋巴结数不存在线性关系（r=0．18，P=0．2）。结论胃周转移淋巴结是一个简单有效判断胃癌术后患者预后的指标。胃周转移淋巴结对淋巴结切除技术要求低，可用于比较不同地区间胃癌术后患者的预后。

Evaluation the value of number of metastatic perigastric lymph nodes on prognosis in patients with gastric cancer

Objective To find out a simple and reprodctive prognostic index in gastric cancer patients, which can be used as a comparable parameter among different regions of China. Methods The perigastric metastatic lymph nodes (PGMLN) with long-term survival data were retrospectively evaluated in 148 gastric cancer patients, undergone potentially curative resections. Results The 3-year cumulative survival rate was 62.8% and the survival rate decreased significantly with the increase of PGMLN, especially when the PGMLN was more than 6. The PGMLN had a clear linear relationship with total positive lymph nodes (r=0.94, P<0.01), while it had little correlation with total resected lymph nodes (r=0.18,P=0.2). Conclusions PGMLN is a convenient and reliable prognostic factor in gastric cancer patients, which may be a good candidate of comparable parameters among different regions of China.