脑梗死与血尿酸水平的关系探讨

目的探讨血尿酸（UA）水平与脑梗死伴颈动脉粥样硬化之间的关系。方法采用彩色多普勒超声分别对85例脑梗死患者和32例健康对照者进行颈动脉检测,同时测定他们的血UA及空腹血糖、总胆固醇、三酰甘油、高密度脂蛋白、低密度脂蛋白水平进行相关性分析。结果脑梗死患者血UA平均水平（389.69±98.28）mmol/L,显著高于对照组（224.51±88.60）mmol/L,两组比较差异有统计学意义（P〈0.01）;脑梗死组伴有颈动脉硬化患者血UA水平（427.31±88.70）mmol/L,高于未伴有颈动脉硬化患者（342.24±78.22）mmol/L,P〈0.05;血尿酸与空腹血糖、总胆固醇、三酰甘油、高密度脂蛋白、低密度脂蛋白无显著相关性,P〉0.05。结论血UA水平与脑梗死、颈动脉粥样硬化有一定相关关系,血UA是独立的致脑梗死危险因素。

Cerebral infarction and the relationship of serum uric acid level

Objective To investigate the serum uric acid（UA）levels and cerebral infarction associated with carotid atherosclerosis relationship.Methods Color Doppler ultrasound were 85 cases of cerebral infarction patients and 32 healthy controls were detected carotid artery were also measured their blood UA and fasting blood glucose,total cholesterol,triglyceride,high-density lipoprotein,low-density lipoprotein level of correlation analysis.Results Of cerebral infarction in patients with UA average（389.69±98.28）mmol/L,were significantly higher（224.51±88.60）mmol/L,The two groups was statistically different（P0.01）.Cerebral infarction associated with carotid artery sclerosis in patients with serum UA levels（427.31±88.70）mmol/L,higher than that associated with carotid atherosclerosis in patients（342.24±78.22）mmol/L（P0.05）.Serum uric acid and fasting blood glucose,total cholesterol,triglyceride,high-densitylipoprotein,LDL no significant correlation（P0.05）.Conclusion In serum UA levels and cerebral infarction,carotid atherosclerosis have a certain correlation between serum UA is an independent risk factor for cerebral infarction induced.