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Magnetic resonance imaging: Comparison of four pulse sequences in assessing primary bone tumours
Authors:Moshe Graif  Jacqueline M. Pennock  Jean Pringle  D. R. Sweetnam  Anthony J. Jelliffe  Graeme M. Bydder  Ian R. Young
Affiliation:(1) Department of Diagnostic Radiology, The Chaim Sheba Medical Centre, Tel Hashomer, Israel;(2) Department of Morbid Anatomy, Institute of Orthopaedics, Stanmore, Middlesex, UK;(3) Department of Orthopaedic Surgery, The Middlesex Hospital, Mortimer Street, London, UK;(4) Department of Oncology, The Middlesex Hospital, Mortimer Street, London, UK;(5) Picker International, Wembley, Middlesex, UK;(6) NMR Unit, Hammer-smith Hospital, Du Cane Road, W12 OHS London, UK
Abstract:A prospective magnetic resonance imaging (MRI) study was carried out in 13 patients (19 examinations) with primary bone tumours to assess the relative value of each of four pulse sequences in showing the extent and nature of the lesion. The four pulse sequences used were a T1-weighted spin-echo (SE544/44), a T2-weighted spin echo (SE1500/80), a short TI inversion recovery (STIR) (IR500/100/44), and a partial saturation (PS) (PS500/22) with field echo data collection. For soft tissue disease the combination of PS and STIR gave better definition of the boundary of the tumour than the more conventional T1 and T2-weighted spin echo sequences. For the demonstration of bone cortex, periosteal change and calcification, T1 and T2-weighted spin echo sequences were better. However, for calcified tissues, plain radiographs were better than either MRI combination. On the assumption that plain films will be available in all cases, PS and STIR sequences could therefore be substituted for T1 and T2-weighted spin echo sequences allowing an increase in soft tissue detectability for lesions in both red and yellow marrow.
Keywords:Magnetic resonance imaging  Pulse sequences  Primary bone tumour
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