Immunoreactive beta-endorphin, cortisol, and growth hormone plasma levels in obsessive-compulsive disorder |
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| Authors: | R Weizman I Gil-Ad H Hermesh H Munitz Z Laron |
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| Affiliation: | Hasharon Hospital, Petah Tiqva, Israel. |
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| Abstract: | Basal morning plasma levels of immunoreactive-beta-endorphin (ir-beta-EP), cortisol, and growth hormone (GH) were assessed in 13 obsessive-compulsive disorder (OCD) patients in comparison to 20 healthy controls. All subjects were drug free for at least 1 year. The mean plasma level of ir-beta-EP was significantly lower (36%) in the OCD patients when compared with the control subjects. The decrease in ir-beta-EP was not accompanied by alteration in cortisol and GH plasma levels. |
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