| Rectosigmoid findings are not associated with proximal colon cancer： Analysis of 6 196 consecutive cases undergoing total colonoscopy |
| |
| 作者姓名： | Okamoto M Kawabe T Yamaji Y Kato J Ikenoue T Togo G Yoshida H Shiratori Y Omata M |
| |
| 作者单位： | Department of Gastroenterology,Department of Gastroenterology,Department of Gastroenterology,Department of Gastroenterology,Department of Gastroenterology,Department of Gastroenterology,Department of Gastroenterology,Department of Gastroenterology,Department of Gastroenterology Faculty of Medicine,University of Tokyo,Japan,Faculty of Medicine,University of Tokyo,Japan,Faculty of Medicine,University of Tokyo,Japan,Faculty of Medicine,University of Tokyo,Japan,Faculty of Medicine,University of Tokyo,Japan,Faculty of Medicine,University of Tokyo,Japan,Faculty of Medicine,University of Tokyo,Japan,Faculty of Medicine,University of Tokyo,Japan,Faculty of Medicine,University of Tokyo,Japan |
| |
| 摘 要： | AIM: To review the risk of proximal colon cancer in patients undergoing colonoscopy. METHODS: We estimated the risk of advanced proximal adenomas and cancers in 6 196 consecutive patients that underwent colonoscopy (mean age 60 years, 65% males, without prior history of colorectal examination). Neoplasms were classified as diminutive adenoma (5 mm or less), small adenoma (6-9 mm), advanced adenoma (10 mm or more, with villous component or high-grade dysplasia) and cancer (invasive adenocarcinoma). The sites of neoplasms were defined as rectosigmoid (rectum and sigmoid colon) and proximal colon (from cecum to descending colon). RESULTS: The trend of the prevalence of advanced proximal adenoma was to increase with severe rectosigmoid findings, while the prevalence of proximal colon cancer did not increase with severe rectosigmoid findings. Among the 157 patients with proximal colon cancer, 74% had no neoplasm in the rectosigmoid colon. Multivariate logistic-regression analysis revealed that age was the main predictor of proximal colon cancer and existence of rectosigmoid adenoma was not a predictor of proximal colon cancer. CONCLUSION: Sigmoidoscopy is inadequate for colorectal cancer screening, especially in older populations.
|
| 关 键 词： | 结肠肿瘤 结肠镜检查 手术入口 耐受性 |
| 收稿时间： | 2004 May 7 |
Rectosigmoid findings are not associated with proximal colon cancer: analysis of 6 196 consecutive cases undergoing total colonoscopy |
| |
| Okamoto M,Kawabe T,Yamaji Y,Kato J,Ikenoue T,Togo G,Yoshida H,Shiratori Y,Omata M.Rectosigmoid findings are not associated with proximal colon cancer: analysis of 6 196 consecutive cases undergoing total colonoscopy[J].World Journal of Gastroenterology,2005,11(15):2249-2254. |
| |
| Authors: | Okamoto Makoto Kawabe Takao Yamaji Yutaka Kato Jun Ikenoue Tsuneo Togo Goichi Yoshida Haruhiko Shiratori Yasushi Omata Masao |
| |
| Institution: | Department of Gastroenterology, Faculty of Medicine, University of Tokyo, Japan |
| |
| Abstract: | AIM:To review the risk of proximal colon cancer in patients undergoing colonoscopy. METHODS: We estimated the risk of advanced proximal adenomas and cancers in 6 196 consecutive patients that underwent colonoscopy (mean age 60 years, 65% males, without prior history of colorectal examination). Neoplasms were classified as diminutive adenoma (5 mm or less), small adenoma (6-9 mm), advanced adenoma (10 mm or more, with villous component or high-grade dysplasia) and cancer (invasive adenocarcinoma). The sites of neoplasms were defined as rectosigmoid (rectum and sigmoid colon) and proximal colon (from cecum to descending colon). RESULTS: The trend of the prevalence of advanced proximal adenoma was to increase with severe rectosigmoid findings, while the prevalence of proximal colon cancer did not increase with severe rectosigmoid findings. Among the 157 patients with proximal colon cancer, 74% had no neoplasm in the rectosigmoid colon. Multivariate logistic-regression analysis revealed that age was the main predictor of proximal colon cancer and existence of rectosigmoid adenoma was not a predictor of proximal colon cancer. CONCLUSION: Sigmoidoscopy is inadequate for colorectal cancer screening, especially in older populations. |
| |
| Keywords: | Colorectal cancer Advanced adenoma Rectosigmoid colon Proximal colon |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ |
|
