| Abstract: | The usefulness of sulfamethizole capsulescontaining contrast medium in gastric emptying tests forfunctional dyspepsia was evaluated in five healthyvolunteers and nine patients with dysmotility-likesymptoms. Each subject swallowed 15 capsules with aliquid, food, and at 0, 15, 30, 45, 60, 90, and 120 min,the capsule position and size were monitoredfluoroscopically for 30 sec and radiograms wereobtained. Blood sulfamethizole concentrations were alsomeasured at the same time. Visualized capsule movementfrom the proximal to distal stomach up to 60 min wasfaster in the patients, whereas in the later digestion period, proximal stomach emptying in thepatients was delayed significantly (P < 0.05), andthe number of capsules remaining in the distal stomachat 120 min was significantly larger in the patients (P < 0.05). This test method was evaluatedas being useful in monitoring solid emptying in normaland pathophysiologic conditions. |
