基于BIOMEMS技术的细胞电阻抗传感器的研究进展

细胞一电阻抗传感器是基于BIOMEMS技术的研究细胞电生理和临床药理研究的新兴工具,主要应用于细胞等微生物体的形态和功能研究.近年来,它以其新颖简单的设计和长时程的无损测试等优点一直受到国内外学者和企业的广泛关注.首先分析细胞一电极阻抗界面模型并加以细化,然后介绍生物阻抗传感器在国际上研究的最新进展.在此基础上,结合实验室当前的研究工作,介绍了自制的基于叉指型细胞电阻抗传感器,最后提出了未来主要发展方向.

Research progress of the cell-impedance sensor based on MEMS technique

The cell-impedance substrate sensor,which is mainly used to detect the shapes and function of cells and other micro.organism.is a novel tool based on the technique of BIOMEMS to study the cellular physiology and clinical Dharmasology.It has drawn attention from both domestic and international scholars as well as compa nies in recent years for its advantages such as innovative design and long-term non-invasive monitoring.This paper introduces the interfacial model of cell-sensor in detail and gives a sketch of the recent international research progress.Then the novel interdigitated array,which was designed in our group recently,is introduced.The fore ground of development is discussed in the end.