代谢综合征与前循环脑梗死相关性的研究

目的 研究代谢综合征(MS)及其各组分与前循环脑梗死(ACI)的关系.方法 ACI组271例,诊断符合<中国脑血管病防治指南>脑梗死牛津郡社区卒中研究分型标准,并经CT或MRI证实;对照组147例,均为门诊健康体检者.观察MS在ACI组和对照组的患病率、MS各组分水平以及MS对ACI的危险度.MS诊断采用修订后的中国人MS诊断标准.结果 ACI组和对照组MS的患病率分别为43.17%和19.05%,两组差异有统计学意义(P<0.01).ACI组MS各组分水平与对照组间差异均有统计学意义(P值均<0.05).MS使ACI发病的危险增加3.7倍(P<0.01).结论 MS与ACI关系密切,MS是ACI的重要危险因素.

A study on the relationship between metabolic syndrome and anterior cerebral infarction

Objective To study the relationship between metabolic syndrome (MS) and anterior circulation infarction (ACI). Methods 271 ACI patients (166 men and 105 women) who fulfilled the diagnostic criteria of China Guideline for Cerebrovascular Disease Prevention and Treatment were enrolled. 147 control subjects (67 men and 80 women) without the clinical signs of cerebral infarction but with detailed case history, physical examination and CT or MRI were also selected. The prevalence and risk of MS were observed in the ACI and control group. MS was defined with the modified criteria in Chinese. Results The prevalence of MS in the ACI group and control subjects was respectively 43.17% and 19.05%. The prevalence of MS was significantly higher in the ACI group as compared with the control subjects (P<0.01). The component level of MS were significandy different between the two groups (P< 0.05). MS was associated with a 3.7 fold higher risk of ACI (P<0.01). Conclusions There is a close relationship between MS and ACI. MS is an important risk factor of ACI.