慢性酒精中毒性胼胝体变性急性期临床诊疗分析

目的探讨慢性酒精中毒性胼胝体变性急性期的治疗措施。方法对15例慢性酒精中毒性胼胝体变性急性期昏迷病例使用大剂量维生素B1治疗，常规减轻脑水肿、神经营养和改善脑血循环治疗，在治疗24、48、72h按照Glasgow’s昏迷评分标准进行神志监测及神经系统体征变化，观察临床治疗效果。结果在治疗72h内，13例患者由昏迷转为神志清醒，Glasgow’s评分达到15分，后遗症减少。结论对慢性酒精中毒性胼胝体变性急性期患者使用大剂量维生素B1治疗，具有使患者尽快苏醒，后遗症减少的临床效果。

Clinical analysis of chronic alcoholic corpus callosum degeneration in acute phase

Objective To investigate the treatment strategies for chronic alcoholic degeneration of the corpus callosum in acute phase. Methods Large doses of vitamin B1 were administrated to 15 patients with chronic alcoholic corpus callosum degeneration in acute coma phrase. Routine treatments aiming at alleviating cerebral edema, nourishing neurons and improving cerebral blood circulation were provided. Glasgow coma score was employed to monitor the consciousness and changes in nerves system 24 h, 48 h and 72 h post the treatment. ResultsTotally 13 out of 15 patients with coma became sober within 72 h after the treatment as Glasgow coma score amounting to 15. Conclusion Administration of high - dosed vitamin B1 is an efficient way to achieve early consciousness and to decrease the aftereffects concerning the cases of chronic alcoholism corpus callosum degeneration in acute phase.