腹腔镜下手术治疗胃肠间质瘤的临床效果观察

目的:分析胃肠间质瘤疾病特点,评价腹腔镜下手术治疗对患者手术情况的影响.方法:选择2018年12月～2019年9月本院诊治的82例胃肠间质瘤疾病患者,获得伦理委员会审核,结合手术方法进行开腹治疗、腹腔镜下手术治疗的对照组与观察组分组,各41例.比较2组胃肠间质瘤疾病患者的手术相关指标、术后应激指标水平以及并发症发生率、...

Observation on the Clinical Effect of Laparoscopic Surgery for Gastrointestinal Stromal Tumors

Objective:To analyze the characteristics of gastrointestinal stromal tumors and evaluate the impact of laparoscopic surgery on patients’surgical conditions.Methods:A total of 82 patients with gastrointestinal stromal tumor disease diagnosed and treated in our hospital from December 2018 to September 2019 were selected and divided into the control group and the observation group,41 cases in each group,who were audited by the ethics committee and underwent laparotomy and laparoscopic surgery combined with surgical methods.Compared the two groups of patients with gastrointestinal stromal tumor disease operation related indicators,postoperative stress index level,complication rate,recurrence and metastasis six months after surgery,treatment effect satisfaction.Results:The comparison of operation related indexes(operation time,intraoperative blood loss and recovery time)between groups showed that the observation group had less intraoperative blood loss and shorter operation and postoperative recovery time(P<0.05).After 24 hours,the levels of stress indexes of cortisol(Cortisol,Cor),interleukin-1(Interleukin-1,IL-1)and tumor necrosis factor-α(TNF-α)in the observation group were compared.The levels of Cor,IL-1 and TNF-αin patients with plasmoma were significantly lower than those in the control group,P<0.05;The postoperative follow-up recurrence and metastasis between the groups showed no significant difference,P>0.05.Comparing the postoperative infection,adhesive intestinal obstruction and other complications between the groups,the incidence rate of the observation group(7.31%)was significantly lower than that of the control group,P<0.05.Conclusion:The long-term effect of laparotomy and laparoscopic surgery in the treatment of gastrointestinal stromal tumor is similar,while laparoscopic surgery has more advantages in surgical trauma,postoperative recovery,safety and high patient satisfaction.