西北高原地区居民骨密度研究

目的探索西北高原地区男性居民骨密度值特点.方法应用法国产UBIS3000超声骨密度仪对生活在海拔2800米及1500米不同高度的高原居民进行大样本骨密度测定,以机内自备之大样本日本人正常值为对照,并对测定值进行统计学分析.结果生活在海拔2800米高原居民骨密度值显著降低,与对照组比较有显著差异(P＜0.01).生活在海拔1500米高原居民骨密度值与对照组比较无明显差异.结论用超声诊断技术(USD)测骨密度值,声量减弱(BUA)值是具有统计意义的重要参考值,声速(SOS)值不具备此特点.生活在海拔2800米高原居民中年轻人(年龄＜29岁者)及在高原生活时间较短者(＜5年)骨密度值降低尤为显著.考虑高原居民骨密度值下降可能与低氧、消化系统功能差及营养不良有关.本研究初步确定了我国西北高原男性居民各年龄段的骨密度值分布范围及特点,为在高原医学领域中进行骨密度研究方面开辟了一个新途径.

Measurement and analysis of bone density of people living on plateau of North-Western area of China

Objective:analyses the characteristics of bone mineral density(BMD) values of people living on plateau of North-Western area of China Methods:The BMD values of large samples of residents living on plateau with height above sea level of 1500 to 2800m were determined by using UBIS 3000 ultrasound bone density instrument (made in France) ,and the Results were compared with normal values of Japanese(data in the densitomiter). Results:The BMD of people living on plateau with height above sea level of 2800m de-creased obviously(P<0.01). There were no obvious difference between the BMD value of people living on plateau with height above sea level of 1500m with the value of control group. Conclusion: Using the technique of ultrasound diagnosis(USD) to measure the bone density,BUA(Broadband Ultrasonic Attenuation)is an im-portant statistic data,SOS(Speed of Sound)is of no characteristic importance. Of the people living on plateau with height above sea level of 2800m, the younger persons( <29 ages) and the people living for shorter periods ( <5 years) had remarkable decrease of bone density. The decrease of BMD perhaps was related with hypoxia, dysfunction of digestive system and malnutrition. This study initially definite the distribution and characteris-tics of bone density of all age ranges in North-Western plateau in China,and it develops a new way to perform bone density study in plateau medical field.