尸体肾移植1011例次的回顾与分析

１９７８年６月至１９９３年１２月，我院完成同种异体肾移植９６９例，１０１１例次。人／肾总存活率１年为８９．２％／７８．７％；３年为８２．０％／７４．７％；５年为６７．０％／５８．４％；存活１０年以上已有１２例，最长存活已达１５年。１５昕的经验表明：（１）高质量取肾与植肾手术尤为重要；（２）由于环孢素在体内的吸收和代谢存在着明显个体差异及受者免疫反应强度不同，监测环孢素血浓度甚为重要；（３）应坚持Ａ

Review and Analysis of 1 011 Cadaveric Renal Transplantation

renal allograft transplants in 969 cases were performed in 15 years, from June, 1978 to December,1993.Patients/grafts survival rates were 89. 2%/78. 7% for 1 year, 82. 0%/74. 7% for 3 years and 67. 0%/58. 4% for 5 years respectively. Twelve cases have survived for more than 10 years. Expereience in renal transplantation in the past 15 years revealed: (1)High quality of procurement and transplantation was of the most important. (2) The monitoring of CsA blood level ABO matching and lymphocytes toxicity assay should be stillpersistent. (3) Infections were the main cause of failure in transplantation. Prevention of infections should be carried out before, after and during operation. (4)Follow-up and directing the treatment during convalescent period must be emphasized.