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尿IL-6监测对肾移植术后急性排斥反应的诊断价值
引用本文:项贵明,李阳,姚磊,朱鹏,蒲晓允. 尿IL-6监测对肾移植术后急性排斥反应的诊断价值[J]. 重庆医学, 2008, 37(17)
作者姓名:项贵明  李阳  姚磊  朱鹏  蒲晓允
作者单位:第三军医大学新桥医院检验科,重庆400037
摘    要:目的探讨肾移植患者手术前后尿液中IL-6的变化及临床意义。方法采用ELISA法,动态监测患者移植手术前后尿液中IL-6的浓度。结果尿液中IL-6的浓度在肾移植术后第1天明显升高。急性排斥反应前1~2天尿液中IL-6的浓度有不同程度的升高,抗排斥治疗后迅速下降。结论动态监测尿IL-6是早期诊断肾移植术后急性排斥反应的一个较好的参考指标。

关 键 词:肾移植  急性排斥反应  白细胞介素-6

Detection of urinary interleukin-6 and its clinical significance to predict acute rejections after renal transplantion
XIANG Gui-ming,LI Yang,YAO Lei,et al.. Detection of urinary interleukin-6 and its clinical significance to predict acute rejections after renal transplantion[J]. Chongqing Medical Journal, 2008, 37(17)
Authors:XIANG Gui-ming  LI Yang  YAO Lei  et al.
Affiliation:XIANG Gui-ming,LI Yang,YAO Lei,et al.(Department of Laboratory,Xinqiao Hosptial,Third Military Medical University,Chongqing 400037,China)
Abstract:Objective To investigate the change of urinary interleukin-6 in the receptors after renal transplantation and to evaluate its contribution to predict acute rejections.Methods The urinary interleukin-6 were detected by enzyme linked immunosorbent assay(ELISA) and its clinical significance was analyzed combined with occurrence of acute rejections.Results Urinary interleukin-6 1 day after transplantation in all receptors was higher than that before transplantation and its level began increasing 1~2 days before...
Keywords:renal transplantation  acute rejection  interleukin-6  
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