ADC值与MR T_1WI最大强化值相关性分析评估肝癌的临床随访价值

目的定量分析原发性及继发性肝癌肿瘤组织的表观扩散系数(ADC)值,探讨MR扩散加权成像(DWI)在临床上评估肝癌患者的治疗疗效及预后的能力。资料与方法对53例肝癌患者行MR DWI、常规平扫T1WI、T2WI和T1WI钆对比剂增强扫描,系统化分析并观察病灶内部存活的肿瘤组织与肿瘤液化坏死组织成分的DWI与增强图像上的信号特征,测量各组信号强度值,并计算出各组ADC值与对应的MR T1WI增强扫描最大强化值,进行统计学相关性分析。结果 MR DWI像上肝癌病灶内残存或复发的肿瘤组织表现为稍高信号,增强扫描显示明显正性强化;液化坏死部分表现为明亮高信号,增强扫描无明显强化;ADC图上肿瘤组织为稍高于正常肝实质的高信号,肿瘤坏死组织部分为低信号;均数ADC值分别为:b=500 s/mm2时,肝癌肿瘤组织约为(1.15±0.43)×10-3mm2/s,肿瘤坏死囊变组织约为(1.88±0.43)×10-3 mm2/s,正常肝实质约为(1.31±0.16)×10-3 mm2/s;b=800 s/mm2时,肝癌肿瘤组织约为(1.02±0.37)×10-3mm2/s,肿瘤坏死组织约为(1.71±0.32)×10-3mm2/s...

Correlations Between ADCs and Maximum T_1WI Enhancement Values in Follow up Evaluating Liver Cancer

Objective To investigate the capability of diffusion weighted imaging(DWI) in assessing the therapeutic effects of liver cancer.Materials and Methods Diffusion weighted imaging and dynamic contrast enhancement MRI were performed in 53 consecutive patients with liver cancer.MRI findings,DW images and apparent diffusion coefficient(ADC) maps were analyzd.ADCs and maximum MR T1 weighted image(T1WI) enhancement values in all lesions were measured and calculated using Student's t test and Pearson correlations.Re...